Lunar II was originally going to carry over the cast of The Silver Star, and its preliminary designs reflect that. Game Arts changed plans, however, and Lunar II got a mostly new lineup of characters. Some characters, including standard-issue protagonist Hiro and gallivanting monk Ronfar, didn’t change all that much from their initial concepts. Other characters did.
One of the biggest alterations: royal knight Leo and his priestess sister Mauri are beast-people in the final game, but they were first designed as centaurs. I suspect this was changed for two reasons. One: Leo would be harder to animate during battles if he were a horse from the waist down. Two: the romance between centaur Mauri and the fully human Ronfar would’ve raised all sorts of questions.
Leo still went through more redesigns, growing less bestial in each phase. That’s his near-final look on the right. Character designer Toshiyuki Kubooka abandoned a more leonine face in favor of a snout and horn.